A manganese requirement for patulin biosynthesis by cultures of Penicillium urticae

✍ Scribed by R. E. Scott; A. Jones; G. M. Gaucher

• Book ID: 104638372
• Publisher: Springer Netherlands
• Year: 1984
• Tongue: English
• Weight: 352 KB
• Volume: 6
• Category: Article
• ISSN: 0141-5492
• DOI: 10.1007/bf00140042

✦ Synopsis

Antibiotic production by submerged cultures of Penicilliwn urtioae required manganese supplementation of the media. Thus, manganese supplementation (152 uM) allowed accumulation of patulin to high concentrations (2 ~mol/mL), whereas manganese deficiency (1.53 ~M) resulted in the accumulation to similar levels of the first committed pathway intermediate, methylsalicylic acid, without significant patulin accumulation. Preliminary studies suggest that a similar manganese effect may occur in other fungal species.