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A malignant peripheral nerve sheath tumor in association with a paratesticular ganglioneuroma

✍ Scribed by Evelyn Banks; Moonahm Yum; Cheryl Brodhecker; Michael Goheen

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 694 KB
Volume: 64
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19891015)64:8<1738::aid-cncr2820640830>3.0.co;2-j

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✦ Synopsis

A malignant peripheral nerve sheath (PNS) tumor and a benign ganglioneuroma were present as a composite tumor in the paratesticular area of a 15-year-old boy. The pathologic diagnosis was made by characteristic histologic and ultrastructural features and was supported by the demonstration of neuron-specific enolase (NSE)-positive ganglion cells and S-100-protein-positive spindle cells consistent with schwannian cells. The patient has remained disease-free for 3 years since the orchiectomy and the retroperitoneal lymph node dissection, which was followed by combination chemotherapy.

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