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Malignant peripheral nerve sheath tumor arising in a “de novo” ganglioneuroma: A case report and review of the literature

✍ Scribed by Drago, Gisela; Pasquier, Basile; Pasquier, Dominique; Pinel, Nicole; Rouault-Plantaz, Veronique; Dyon, Jean-François; Durand, Chantal; Armari-Alla, Corinne; Plantaz, Dominique

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
923 KB
Volume
28
Category
Article
ISSN
0098-1532

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✦ Synopsis

A case of a "de novo" ganglioneuroma show-that, although rare, the spontaneous developing a large area of malignant peripheral nerve ment of an MPNST in a benign ganglioneuroma sheath tumor (MPNST) is described. The tumor can occur. Immunohistochemical and electron arose in an 11.5-year-old girl with neither stig-microscopy studies supported the finding that mata nor family history of von Recklinghausen's the spindle cell component was of nerve sheath neurofibromatosis. In addition, the patient had origin. Med. Pediatr. Oncol. 28:216-222 no previous history of a neuroblastoma or radia-ᮊ 1997 Wiley-Liss, Inc.

tion therapy. This report provides new evidence Key words: ganglioneuroma; neuroblastoma; malignant peripheral

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