Peripheral nerve tumors involving paranasal sinuses: A case report and review of the literature

✍ Scribed by Yvon Robitaille; Thomas A. Seemayer; A. El Deiry

• Publisher: John Wiley and Sons
• Year: 1975
• Tongue: English
• Weight: 510 KB
• Volume: 35
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197504)35:4<1254::aid-cncr2820350433>3.0.co;2-3

✦ Synopsis

A 45-year-old man, afflicted with von Recklinghausen's disease, with symptomatic schwannomas and plexiform neurofibromas involving the right maxillary antrum, a rare site for peripheral nerve tumors, is presented. After a literature review, 15 cases were considered adequate for a clinicopathologic study. Twelve schwannomas, 2 plexiform neurofibromas, 2 neurofibromas, and 1 probable malignant schwannoma were included. Epistaxis was common in tumors of the ethmoid sinus and nasal fossae, while pain was related to lesions of the maxillary sinus. Two benign schwannomas recurred and were cured by surgery alone. The importance of early diagnosis and thorough surgical excisions is emphasized, especially for those tumors associated with von Recklinghausen's disease. The difficulties involved in the diagnosis of primary malignant peripheral nerve tumors are discussed. Cancer 35:1254-1258, 1975. RIMARY NEUROGENIC TUMORS ARISING IN P the paranasal sinuses are rare entities. Kragh et al. reviewed 152 neurilemmomas of the head and neck covering a period from 1910 through 1957, of which 148 were benign and 4 malignant." None of the malignant tumors arose in the paranasal sinuses. Of the benign tumors only 1 was reported to involve paranasal sinuses. We recently had the opportunity to investigate a patient with von Recklinghausen's neurofibromatosis, who presented with multiple schwannomas and plexiform neurofibromas of the maxillary antrum. The documentation of this presentation, combined with a review of peripheral nerve tumors arising in the paranasal sinuses, form the basis of this report.

CASE REPORT

A 45-year-old man with documented von Recklinghausen's disease was referred to the Royal Victoria Hospital in 1973 because of recurrent pain and fullness in the right cheek.