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A Luminescent Sensor for Tyrosine Phosphorylation

✍ Scribed by Tremblay, Matthew S.; Lee, Minhee; Sames, Dalibor

Book ID
126795852
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
217 KB
Volume
10
Category
Article
ISSN
1523-7060

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The tubulin tyrosination/detyrosination cycle is a well-established posttranslational modification, which is carried out by two enzymes: Tubulin Tyrosine Ligase (TTL) and Tubulin Tyrosine Carboxypeptidase (TTCP). In this paper, I present evidence suggesting that the cycle itself is under the hierarc