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Negative Regulation of a Protein Tyrosine Phosphatase by Tyrosine Phosphorylation

✍ Scribed by Schwarzer, Dirk; Zhang, Zhongsen; Zheng, Weiping; Cole, Philip A.


Book ID
126890554
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
110 KB
Volume
128
Category
Article
ISSN
0002-7863

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The regulation of tyrosine phosphorylation represents a key mechanism governing cell proliferation. In fibroblasts, inputs from both growth factor and extracellular matrix receptors are required for cell division. Triggering such receptors induces a wave of tyrosine phosphorylation on key signaling