✦ LIBER ✦

A kinetic model for the action of the enzyme activated irreversible inhibitor 4-amino-5-hexynoic acid in vivo

✍ Scribed by Ian T. Carney; Susan A. Miller; John M. Basford; Robert A. John

Book ID: 115777343
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 583 KB
Volume: 33
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(84)90038-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pulse Experiments as a Prerequisite for

Pulse Experiments as a Prerequisite for the Quantification of in Vivo Enzyme Kinetics in Aromatic Amino Acid Pathway of Escherichia coli

✍ M. Schmitz; E. Hirsch; J. Bongaerts; R. Takors 📂 Article 📅 2002 🏛 American Institute of Chemical Engineers 🌐 English ⚖ 176 KB

THE EFFECT OF 4-AMINO HEX-5-YNOIC ACID (

THE EFFECT OF 4-AMINO HEX-5-YNOIC ACID (γ-ACETYLENIC GABA, γ-ETHYNYL GABA) A CATALYTIC INHIBITOR OF GABA TRANSAMINASE, ON BRAIN GABA METABOLISM IN VIVO

✍ M. J. Jung; B. Lippert; B. W. Metcalf; P. J. Schechter; P. Böhlen; A. Sjoerdsma 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 636 KB

Further Studies with the 2-Amino-1,3-thi

Further Studies with the 2-Amino-1,3-thiazol-4(5H)-one Class of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Reducing Pregnane X Receptor Activity and Exploring Activity in a Monkey Pharmacodynamic Model

✍ Fotsch, Christopher; Bartberger, Michael D.; Bercot, Eric A.; Chen, Michelle; Cu 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 441 KB

The γ-secretase inhibitor 2-[(1R)-1-[(4-

The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1–42 seeding and short-term memory deficits in the Aβ25–35 mouse model of Alzheimer's disease

✍ Meunier, Johann; Villard, Vanessa; Givalois, Laurent; Maurice, Tangui 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 672 KB

ATP-Citrate Lyase as a Target for Hypoli

ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. 2. Synthesis and Evaluation of (3 R *,5 S *)-ω-Substituted-3-carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in Vitro and in Vivo

✍ Gribble, Andrew D.; Ife, Robert J.; Shaw, Antony; McNair, David; Novelli, Christ 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 275 KB

ChemInform Abstract: ATP-Citrate Lyase a

ChemInform Abstract: ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. Part 2. Synthesis and Evaluation of (3R*,5S*)-ω-Substituted-3-carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in vitro and in vivo.

✍ A. D. GRIBBLE; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. Part 2. Synthesis and Evaluation of (3R\*,5S\*)-ω-Substituted-3carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in vitro and in vivo. -A series of the title compounds is synthesized and evalua