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A-Kinase Anchoring Protein Targeting of Protein Kinase A and Regulation of HERG Channels

โœ Scribed by Yan Li; Jakub Sroubek; Yamini Krishnan; Thomas V. McDonald


Book ID
105926678
Publisher
Springer
Year
2008
Tongue
English
Weight
547 KB
Volume
223
Category
Article
ISSN
0022-2631

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## Abstract Protein scaffold complexes are a key mechanism by which a common signaling pathway can serve many different functions. Sequestering a signaling enzyme to a specific subcellular environment not only ensures that the enzyme is near its relevant targets, but also segregates this activity t