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A High-Throughput Yeast Assay Identifies Synergistic Drug Combinations

โœ Scribed by Torres, Nikko P.; Lee, Anna Y.; Giaever, Guri; Nislow, Corey; Brown, Grant W.


Book ID
121211827
Publisher
Mary Ann Liebert
Year
2013
Tongue
English
Weight
806 KB
Volume
11
Category
Article
ISSN
1540-658X

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โœ Ellyn Farrelly; M.Catherine Amaral; Lisa Marshall; Shu-Gui Huang ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 112 KB

A fluorometric assay for mitochondrial membrane potential in permeabilized yeast cells has been developed. This method involves permeabilizing the plasma membrane and measuring the distribution of a mitochondrial membrane potential sensitive probe 3,3dipropylthiadicarbocyanine iodide (DiSC 3 (5); Di