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A high throughput and selective method for the estimation of valproic acid an antiepileptic drug in human plasma by tandem LC–MS/MS

✍ Scribed by Deepak S. Jain; Gunta Subbaiah; Mallika Sanyal; Pranav Shrivastav


Book ID
116902165
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
551 KB
Volume
72
Category
Article
ISSN
0039-9140

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## Abstract A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method has been developed and validated for the estimation of amlodipine in human plasma. Amlodipine was extracted from human plasma by using a solid‐phase extraction technique. Imipramine was used as the in