A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a
Development and validation of an improved high-throughput method for the determination of anastrozole in human plasma by LC–MS/MS and atmospheric pressure chemical ionization
✍ Scribed by Constantinos Apostolou; Yannis Dotsikas; Constantinos Kousoulos; Yannis L. Loukas
- Book ID
- 108189556
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 563 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0731-7085
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A sensitive and specific LC/MS/MS method for the determination of L-hyoscyamine was developed and validated over the linearity range 20-500 pg ml-1 with 1.0 ml of plasma using scopolamine as the internal standard. The API III-Plus LC/MS/MS was operated under the multiple reaction monitoring mode usi
## Abstract An ultra‐sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the analysis of oral contraceptive ethinyl estradiol (EE) was developed and validated over the curve range of 2.5–500 pg/mL using 1 mL of human plasma sample. Ethinyl estradiol and the internal stand