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A high performance liquid chromatography–tandem mass spectrometric method for the determination of mefenamic acid in human plasma: application to pharmacokinetic study

✍ Scribed by Mahadeo Mahadik; Sunil Dhaneshwar; Ravindra Bhavsar


Book ID
112013428
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
186 KB
Volume
26
Category
Article
ISSN
0269-3879

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Liquid chromatography-tandem mass spectr
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## Abstract A rapid LC‐MS/MS method for quantification of an enaminone analog, E121 in mouse plasma using E118 as an internal standard (IS) has been developed and validated. The analyte was analyzed on C~18~ column using a mobile phase of acetonitrile/methanol/ammonium acetate/formic acid (60:20:20