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Determination of cefazedone in human plasma by high performance liquid chromatography–tandem mass spectrometry: Application to a pharmacokinetic study on Chinese volunteers

✍ Scribed by Dan Wu; Zhen-yu Qian; Tingting Guo; Wenyan Tang; Yi Xiang; Heng Zheng

Book ID
108161213
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
294 KB
Volume
878
Category
Article
ISSN
1873-376X

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## Abstract A rapid and sensitive LC/MS/MS assay was developed and validated for the determination of clopidogrel in human plasma. Clopidogrel was extracted by single liquid–liquid extraction with pentane, and chromatographic separations were achieved on a C~18~ column. The method was validated to