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A high-level prokaryotic expression system: synthesis of human interleukin 1α and its receptor antagonist

✍ Scribed by Klara R. Birikh; Ekaterina N. Lebedenko; Irina V. Boni; Yuri A. Berlin


Book ID
116133048
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
522 KB
Volume
164
Category
Article
ISSN
0378-1119

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Human monocytes induced with adherent IgG secrete an interleukin-1 receptor antagonist which could be important for the in vivo regulation of IL-1 activity. A complementary DNA for this molecule has been isolated from a human monocyte library. Analysis of monocyte RNA indicates that the gene is tran