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A genetic map of microsatellite markers on rat Chromosome 7

✍ Scribed by Y. Du; E. F. Remmers; H. Zha; E. A. Goldmuntz; J. Szpirer; C. Szpirer; R. L. Wilder

Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
436 KB
Volume
6
Category
Article
ISSN
0938-8990

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✦ Synopsis

Nine microsatellite loci were mapped to rat Chromosome (Chr) 7 by genetic linkage and somatic cell hybrid analysis. These loci include the gene encoding a member of the IID subfamily of cytochrome P450 (Cyp2d), a gene with repetitive sequences expressed during myotube formation (D7Arble), four anonymous loci, D7Arb81, D7Arb208, DTArb569, D7Arb609a, and three DNA loci defined by MapPair TM markers R245, R513, and R1071. The nine loci were all identified by PCR-based microsatellite polymorphism analysis and were characterized in 40 F 2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rats for segregation analysis. These markers formed a single linkage group spanning 76.8 cM with the following order and distances:

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