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A General Methodology for Automated Solid-Phase Synthesis of Depsides and Depsipeptides. Preparation of a Valinomycin Analogue †

✍ Scribed by Kuisle, Oliver; Quiñoá, Emilio; Riguera, Ricardo


Book ID
126062178
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
188 KB
Volume
64
Category
Article
ISSN
0022-3263

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## Abstract In this paper we describe the synthesis of chiral peptide nucleic acids (PNAs) 1–3 using SPPS methodologies. Starting material for the monomer units was the commercially available amino acid ornithine. l‐ or D‐ornithine and the nucleobase thymine were linked by a carboxymethylene spacer