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A gas chromatographic/mass spectrometric screening, confirmation, and quantification method for estrogenic compounds

✍ Scribed by Thomas R. Covey; Dominique Silvestre; Michael K. Hoffman; Jack D. Henion

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
974 KB
Volume
15
Category
Article
ISSN
1076-5174

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✦ Synopsis

A method is described for the screening, quantification and confirmation of a variety of estronenic substances in animal tissues. A solid-phase extraction technique combined with a liquid/liquid extraction allows for rapid sample preparation and high throughput for the following compounds in bovine liver, muscle and kidney: diethylstilbestrol, dienestrol, hexestrol, zeranol, taleranol, zearalanone, zearalenone, zearalenol, estradiol and estriol. Gas chromatography/mass spectrometry and selected ion monitoring is used for the determination with detection limits ranging from 50 to 150 ppt.

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