𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A frequent hMSH2 mutation in hereditary non-polyposis colon cancer syndrome

✍ Scribed by NicolaJ Froggatt; JohannaA Joyce; Rhodri Davies; D Gareth; BruceA.J Ponder; DavidE Barton; EamonnR Maher; R Evans

Book ID
118557932
Publisher
The Lancet
Year
1995
Tongue
English
Weight
162 KB
Volume
345
Category
Article
ISSN
0140-6736

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

hMLH1, hMSH2 and hMSH6 mutations in here
hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from Southern Sweden
✍ Maria Planck; Anjila Koul; Eva Fernebro; Γ…ke Borg; Ulf Kristoffersson; HΓ₯kan Ols πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 101 KB πŸ‘ 2 views

We have screened 17 Southern Sweden individuals/families with suspected hereditary non-polyposis colorectal cancer (HNPCC) for mutations in the DNA-mismatch repair genes hMLH1, hMSH2 and hMSH6 using denaturing gradient gel electrophoresis, protein truncation test and direct DNA sequencing. The famil

Predominant germ-line mutation of the hM
Predominant germ-line mutation of the hMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds
✍ Yun-Qing Bai; Yoshimitsu Akiyama; Hiromi Nagasaki; Shi-Long Lu; Takehiro Arai; T πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 113 KB πŸ‘ 2 views

By means of PCR-SSCP and direct sequencing, we detected 12 germ-line mutations of hMSH2 or hMLH1 in 37 Japanese hereditary non-polyposis colorectal cancer (HNPCC) kindreds, of whom 15 satisfied the Amsterdam and 22 the Japanese criteria. The germ-line mutation detection rate of hMSH2 was much higher