✦ LIBER ✦

A freeze dried formulation for the preparation of 99mTc-[V]-DMS complex

✍ Scribed by E. Chiotellis; A. Varvarigou; S. Archimandritis; E. Gyftaki

Publisher: John Wiley and Sons
Year: 1989
Tongue: French
Weight: 404 KB
Volume: 27
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580271007

No coin nor oath required. For personal study only.

✦ Synopsis

A freeze dried kit formulation for the preparation of 999c-[V]-DMS complex was developed, requiring a single step labeling procedure. Methods of analysis were also developed permitting identification of radiochemical impurities which may be resent in radiopharmaceutical solution. FjgmTc-[V]-DMS prepared by the kit method was evaluated in experimental animals and human volunteers. Data demonstrated that the complex formed after kit reconstitution shows tumor seeking properties. Thyroid medullary carcinoma in patients was successfully detected 2 hrs post administration.

📜 SIMILAR VOLUMES

Radiopharmaceutical development of a fre

Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis

✍ Elisabeth Von Guggenberg; Renata Mikolajczak; Barbara Janota; Georg Riccabona; C 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

99m Tc-EDDA-HYNIC-D-Phe 1 ,Tyr 3 ]-Octreotide ( 99m Tc-EDDA/HYNIC-TOC) is a promising new radiopharmaceutical with the potential to replace [ 111 In-DTPA-D-Phe 1 ]-Octreotide ( 111 In-DTPA-OCT) as the radiopharmaceutical for somatostatin receptor scintigraphy due to the advantage of improved image

Radiopharmaceutical development of a fre

Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr 3]-octreotide, a somatostatin analog for tumor diagnosis

✍ Von Guggenberg, Elisabeth (author);Mikolajczak, Renata (author);Janota, Barbara 📂 Article 📅 2004 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 150 KB

A glass apparatus for the preparation of

A glass apparatus for the preparation of freeze-dried samples for SEM

✍ Kingsley, R. E. 📂 Article 📅 1991 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 202 KB

Application of a macromolecular Sn (II)

Application of a macromolecular Sn (II) complex to the preparation of 99mTc radiopharmaceuticals

✍ Morio Nakayama; Takaaki Terahara; Masao Wada; Kumiko Harada; Atsushi Sugii; Hiro 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 405 KB

To develop insoluble Sn2+ complexes for the preparation of 99mTc radiopharmaceuticals, the adsorption of Sn2+ to macroreticular chelating ion exchange resins having various functional groups was investigated. Among them, a resin containing aminophosphonic acid groups showed a high adsorption capacit

Technetium-99m labeling and freeze-dried

Technetium-99m labeling and freeze-dried kit formulation of levofloxacin (L-Flox): a novel agent for detecting sites of infection

✍ E. A. El-ghany; A. M. Amin; O. A. El-kawy; Magdy Amin 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 141 KB

## Abstract In this study, the labeling method of levofloxacin with technetium‐99m and its biological evaluation were described. ^99m^Tc‐L‐Flox was synthesized via direct complexation with technetium‐99m in the presence of stannous chloride dihydrate as reducing agent. The optimum amounts of the re

Preparation, quality control and stabili

Preparation, quality control and stability of 99mTc-sparafloxacin complex, a novel agent for detecting sites of infection

✍ M. A. Motaleb 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 119 KB

## Abstract Labeling of sparafloxacin with technetium‐99m using stannous chloride as a reducing agent was investigated. Dependence of the yield of ^99m^Tc‐sparafloxacin complex on the concentration of sparafloxacin, reducing agent, pH and reaction time was studied. Under optimum conditions, the lab