A formal synthesis of brassinolide

✍ Scribed by T. Schmittberger; D. Uguen

• Book ID: 104256839
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 256 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00474-7

✦ Synopsis

Enzyme-catalysed differentiation of hydroxy groups in a C2v-shaped tetraol-sulfide, combined with a E-stereoconvergent Ramberg-Backlund process, allowed to prepare pure (2S)-2,3-dimethyl-1iodobatane, which could be coupled with a 3,5-cyclopregnane-20-thioracthanol derivative so as to give an e Ofcient precursor of the title vegetal hormone.