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A fluorimetric assay of the phosphoribosylation of 6-mercaptopurine in human blood cells

โœ Scribed by P.C.P. Wong; Y. Hey; J.S.L. Fowler


Book ID
115822589
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
668 KB
Volume
99
Category
Article
ISSN
0009-8981

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A highly sensitive and rapid assay for the detection of 6-mercaptopurine metabolites in the red blood cells-of leukemic patients receiving the drug has been developed. The method employs a batchchromatographic procedure using a mercurial cellulose resin to selectively absorb thiol compounds combined