A first total synthesis of Germacrone by intramolecular alkylation of protected cyanohydrin
โ Scribed by Takashi Takahashi; Kyoko Kitamura; Hisao Nemoto; Jiro Tsuji; Iwao Miura
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 217 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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Dehydroxy-trans-resorcylide (15) was synthesized by efficient intra-molecular alkylation of the protected cyanohydrin. The butadiene telomer obtained by the palladium catalyzed reaction of butadiene with acetic acid was used as a suitable building block of the carbocycle. A number of naturally occ
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