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A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

โœ Scribed by Arany, Zoltan; Newsome, David; Oldread, Elizabeth; Livingston, David M.; Eckner, Richard

Book ID
109791300
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
469 KB
Volume
374
Category
Article
ISSN
0028-0836

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The adenoviral E1A proteins have been implicated in promotion of proliferation and transformation, inhibition of differentiation, induction of apoptosis, regulation of transcription, and suppression of tumor growth. The ability of E1A to override the fundamental controls of host cells is based on it