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The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A

✍ Scribed by Lavender, Paul; Vandel, Laurence; Bannister, Andrew J; Kouzarides, Tony

Book ID
110060844
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
840 KB
Volume
14
Category
Article
ISSN
0950-9232

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## Abstract Several proteins with important roles in oncogenesis have been shown to regulate the function of the E2F‐1 transcription factor, which is known to activate the expression of genes required for proliferation and apoptosis. Here we identify the MDMX oncoprotein as an E2F‐1‐binding factor,