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A Facile Synthesis of Symmetrical and Unsymmetrical Bis(indolyl)acetamides Mediated by Protic Acid

โœ Scribed by Cheng, Mao-Sheng; Chen, Hong; Hao, Fei-Yue; Pan, Li; Shang, Hai

Book ID
118275829
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
681 KB
Volume
83
Category
Article
ISSN
0385-5414

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ChemInform Abstract: A Facile Synthesis
ChemInform Abstract: A Facile Synthesis of Symmetrical and Unsymmetrical Bis(indolyl)acetamides Mediated by Protic Acid.
โœ Hai Shang; Fei-Yue Hao; Li Pan; Hong Chen; Mao-Sheng Cheng ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons โš– 44 KB ๐Ÿ‘ 1 views

## Abstract Dimerization of hydroxyindolylacetamides (I) and (V) leads to formation of symmetrical bis(indolyl)acetamides (II) and (VI), resp., while electrophilic substitution of indoles (III) and (VII) with indolylacetamides (I) give rise to unsymmetrical bis(indolyl)acetamides (IV) and (VIII).