A New Catalytic Application of a Keggin Acid in the Synthesis of Symmetrical Bis(indolyl)alkanes.
✍ Scribed by Manas Chakrabarty; Ajanta Mukherji; Sulakshana Karmakar; Shiho Arima; Yoshihiro Harigaya
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 23 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract Dimerization of hydroxyindolylacetamides (I) and (V) leads to formation of symmetrical bis(indolyl)acetamides (II) and (VI), resp., while electrophilic substitution of indoles (III) and (VII) with indolylacetamides (I) give rise to unsymmetrical bis(indolyl)acetamides (IV) and (VIII).
## Abstract A new __C__~2~‐symmetric chiral catalyst 3,5‐bis[(2__S__)‐(hydroxy‐diphenylmethyl)‐ pyrrolidin‐1‐ylmethyl]‐1,3,4‐oxadiazole was successfully synthesized by the reaction of 2,5‐dichloromethyl‐1,3,4‐oxadiazole with (__S__)‐α,α‐diphenyl‐2‐pyrrolidinemethanol, and applied to the catalytic a