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ChemInform Abstract: A Facile Synthesis of Symmetrical and Unsymmetrical Bis(indolyl)acetamides Mediated by Protic Acid.

✍ Scribed by Hai Shang; Fei-Yue Hao; Li Pan; Hong Chen; Mao-Sheng Cheng

Publisher
John Wiley and Sons
Year
2011
Weight
44 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

Dimerization of hydroxyindolylacetamides (I) and (V) leads to formation of symmetrical bis(indolyl)acetamides (II) and (VI), resp., while electrophilic substitution of indoles (III) and (VII) with indolylacetamides (I) give rise to unsymmetrical bis(indolyl)acetamides (IV) and (VIII).

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