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A facile synthesis of acid-esters

โœ Scribed by Sudhakar Kasina; Jay Nematollahi


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
289 KB
Volume
19
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


We have reportedly2 that 1,1-dimethylhydrazine reacts with various dimethyl esters (vicinal and nonvicinal) to effect monodemethylation; providing a facile method for the synthesis of acid-esters.

This report is the result of our investigation on the monodemethylation of a series of polycarboxylates,


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A general synthesis of 1,3-diaryl-4-pyrazoleacetic acid esters has been realized via the condensation of a ฮณ-carboxy ester hydrazone with the Vilsmeier reagent.