A Facile Silyl Linker Strategy for the Solid-Phase Synthesis of Protected Glycopeptide: Synthesis of an N-Terminal Fragment of IL-2 (1–10)
✍ Scribed by Akira Ishii; Hironobu Hojo; Aki Kobayashi; Kazuhiko Nakamura; Yuko Nakahara; Yukishige Ito; Yoshiaki Nakahara
- Book ID
- 108370918
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 178 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The application of the N-1- (4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) linker for the solid-phase synthesis of oligosaccharides is described. The oligosaccharide products can be cleaved from the resin by hydrazine, ammonia or primary amines, but the linker is stable under the conditions of o
The active ester ilP-Rnoc-3-o\_IAc~~-o-Manp-(l~2)-Ac~ar-D-Manpl-J-~r-O-Pfp (6) was synthesized by direct condensation of Aqor-D-Mmp-(l-2)-Ac=ar-D-h&p-Br (4) with l+noc-Thr-0-m (5) and used as a buikiing block in an automated continwus-flow solid-phase synthesis of an 0-glycosylated heptadeca amino a