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A facile preparation of alkyl α-glycosides of the methyl ester of N-acetyl-d-neuraminic acid

✍ Scribed by Dominicus J.M. van der Vleugel; Wolfgang A.R. van Heeswijk; Johannes F.G. Vliegenthart


Book ID
108308984
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
637 KB
Volume
102
Category
Article
ISSN
0008-6215

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A facile method for the N-alkylation of
✍ W. Russell Bowman; Daniel R. Coghlan 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 853 KB

Monoalkylation of the a-amino group of or-amino acid derivatives can be facilitated using 2and 4-nitrophenylsulfonamide intermediates. The nitrophenylsulfonamides of a-amino esters can be alkylated using an equimolar amount of carbonate base and a variety of alkyl bromides. Ready removal of the nitr