𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A facile one pot synthesis of 2, 4-diamino-6-substituted s-triazine derivatives

✍ Scribed by Ramadas Sathunuru; Victor Melendez; Michael P. Kozar; Ai J. Lin

Publisher
Journal of Heterocyclic Chemistry
Year
2008
Tongue
English
Weight
269 KB
Volume
45
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

magnified image

A novel and facile one‐pot procedure for the preparation of 2,4‐diamino‐6‐substituted‐s‐triazine derivatives (IIa‐n) was reported. The scope of its application was demonstrated with a number of examples. The new procedure involved treatment of proguanil or chloroproguanil with acyl chloride or alky chlorooxoacetate in pyridine at ice cold temperature followed by reflux overnight to give good yields of the desired products.

📜 SIMILAR VOLUMES

Facile synthesis of 2,4-diamino-6-alkyl-
Facile synthesis of 2,4-diamino-6-alkyl- or 6-aryl-pyrimidine derivatives
✍ Xihong Wang; Ramadas Sathunuru; Victor Melendez; Michael P. Kozar; Ai J. Lin 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 126 KB 👁 1 views

## Abstract magnified image Facile methods were developed to prepare a series of 6‐phenyl and 6‐alkyl‐2,4‐diaminopyrimidine derivatives. The pyrimidine ring of the final products was constructed by treatment of a 1,3‐dicarbonyl derivative with an amidine or guanidine. The 6‐phenyl‐pyrimidine deriva

A facile one-pot synthesis of novel subs
A facile one-pot synthesis of novel substituted 1,2,3,4-tetrahydropyrimidines
✍ Enamul Karim; Kaushal Kishore; Jai N. Vishwakarma 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 28 KB 👁 1 views

## Abstract A facile one‐pot synthesis of 5‐benzoyl‐6‐methylthio‐1,2,3,4‐tetrahydropyrimidines in good yields is reported.