A facile conversion of dialkyl phosphonates to dialkyl phosphorodithioates
β Scribed by Takeshi Wada; Tsujiaki Hata
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 140 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Dialkyl phosphonates were converted into the corresponding. phosphorodithioates in three steps by one-pot procedure.
The reaction was applied to the synthesis of nucleoside phosphorodithioate derivatives.
π SIMILAR VOLUMES
## Abstract A new and facile method of synthesis of 1βacetoxyvinyl phosphonates (__2__) has been found. Dialkyl phosphites react readily with acetic anhydride in acetonitrile solution in the presence of catalysts to produce __2__ and acylphosphonates (__1__) as a minor product. The most efficient c
Polycondensation of 1,10-decanediol with dimethyl-H-phosphonate taken in excess leads to oligomers with methyl-H-phosphonate end groups. The polytransesterification of the resulting oligomer as well as the related model reactions were studied. The synthesis of poly(decamethylene-H-phosphonate) was a
For the investigation of biological activities of trifluoromethylated heterocyclic compounds bearing a phosphoryl moiety, a series of N-aryliminophosphonates were obtained by reaction of dialkyl 1methoxycarbonylmethylphosphonates with trifluoroacetimidoyl chlorides using NaH as a deprotonating agent
p-Nitrobenzyl phosphonate anion with p-nitrocumyl halides gives a good yield of the coupling product dialkyl[(1,1-dimethyl-l,2-di-(p-nitrobenzyl)ethyl] phosphonates through the S~N1 mechanism. The reaction was greatly accelerated by sunlamp irradiation but inhibited by the radical scavenger (t-Bu)2N