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A facile and practical synthesis of the derivatives of 1-O-acetyl-2-deoxy-2-hydroxymethyl-D-erythrooxetanose, a key sugar moiety for the synthesis of oxetanosyl-N-glycoside

✍ Scribed by Nagai Masashi; Kato Kuniki; Takita Tomohisa; Nishiyama Shigeru; Yamamura Shosuke


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
108 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis


Intramolecular cyclization of the epoxy-alcohol (6) with predominantly the oxetane compound (7). which could be transformed into oxetanoses. Recently. we have reported the total synthesis of oxetanocin (3),1 KOH in aq. DMSO gave


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Synthesis of O-(2-acetamido-2-deoxy-Ξ²-d-
✍ Rexford L. Thomas; Rashmi Dubey; Saeed A. Abbas; Khushi L. Matta πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 English βš– 934 KB

Condensation of 3-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D- glucopyranosyl)-2,4,6-tri-O-acetyl-alpha-D-galactopyranosyl bromide (1) with benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-alpha-D-glucopyranoside in boiling benzene and in the presence of mercuric cyanide afforded a trisaccharide that