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A Disruption Mechanism of the Molecular Clock in a MPTP Mouse Model of Parkinson’s Disease

✍ Scribed by Akane Hayashi, Naoya Matsunaga, Hiroyuki Okazaki…

Book ID
120897986
Publisher
Humana Press Inc
Year
2013
Tongue
English
Weight
715 KB
Volume
15
Category
Article
ISSN
1535-1084

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o