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A direct role for DNA polymerase III in adaptive reversion of a frameshift mutation in Escherichia coli

✍ Scribed by Reuben S Harris; Harold J Bull; Susan M Rosenberg


Book ID
114071166
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
166 KB
Volume
375
Category
Article
ISSN
0027-5107

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A tenfold increase in the spontaneous reversion frequency of two of six lacZ frameshift mutations tested was observed in strains containing the following DNA polymerase I mutations--polA1, polA5, polA6, polAex1, res-3 and resA1. Reconstruction experiments indicated that this increase was not the res