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A direct, highly convergent route to α-methylene-γ-lactones fused to medium and large rings

✍ Scribed by Leo A. Paquette; José Méndez-Andino

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 204 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00781-9

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✦ Synopsis

A general procedure for the synthesis of a-methylene lactones cis-or trans-fused to larger rings is described. The convenient approach originates with two co-unsaturated aldehydes of the same or different chain length.

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