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A differential pulse polarographic assay for O-methylation of catechols by catechol-O-methyltransferase

โœ Scribed by Larry A. Sternson; Arlene W. Sternson; Steve J. Bannister


Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
611 KB
Volume
75
Category
Article
ISSN
0003-2697

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A new assay technique for catechol-0-methyltransferase is described. 3,4-Dihydroxyacetophenone is used as the substrate for the assay and the products, 3-hydroxy-4-methoxyacetophenone and 4-hydroxy-3-methoxyacetophenone are detected spectrophotometrically at 344 nm in borate buffer, pH 10.0. This sp