✦ LIBER ✦

A differential PCR system for the determination of CCND1 (Cyclin D1) gene amplification in head and neck squamous cell carcinomas

✍ Scribed by Christian Schneeberger; Sabine Eder; Herwig Swoboda; Robert Ullrich; Robert Zeillinger

Book ID: 114394331
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 478 KB
Volume: 34
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(98)80004-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PRAD-1 (CCND1)/Cyclin D1 oncogene amplif

PRAD-1 (CCND1)/Cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma

✍ Troy Callender; Adel K. El-Naggar; Ming S. Lee; Robert Frankenthaler; Mario A. L 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 657 KB

## Background. Abnormalities in chromosome llq13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCNDI), which encodes cyclin D1, is a putative oncogene that is an important component of this region. Methods. DNA was extracted

Heterogeneity of the proliferative fract

Heterogeneity of the proliferative fraction and cyclin D1/CCND1 gene amplification in head and neck squamous cell carcinoma

✍ Adel K. El-Naggar; Kim Steck; John G. Batsakis 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 537 KB

Cyclin D1 amplification is independent o

Cyclin D1 amplification is independent of p16 inactivation in head and neck squamous cell carcinoma

✍ Okami, K; Reed, A L; Cairns, P; Koch, W M; Westra, W H; Wehage, S; Jen, J; Sidra 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 217 KB

Amplification of cyclin D1 in squamous c

Amplification of cyclin D1 in squamous cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 overexpression

✍ Jan A. Åkervall; Rob J. A. M. Michalides; Hiroyuki Mineta; Alfons Balm; Åke Borg 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB 👁 2 views

## Background: Abnormalities of chromosome band 11q13 are frequent in squamous cell carcinoma of the head and neck (scchn). the oncogene ccnd1 is located at 11q13 and encodes cyclin d1, a cell cycle-regulating protein. the authors investigated the clinical relevance and associations between amplifi

Cyclin D1 Polymorphism and Expression in

Cyclin D1 Polymorphism and Expression in Patients with Squamous Cell Carcinoma of the Head and Neck

✍ Sarah L. Holley; Gary Parkes; Christoph Matthias; Ulrike Bockmühl; Volker Jahnke 📂 Article 📅 2001 🏛 American Society for Investigative Pathology 🌐 English ⚖ 187 KB

Cyclin-D1-gene amplification is a more p

Cyclin-D1-gene amplification is a more potent prognostic factor than its protein over-expression in human head-and-neck squamous-cell carcinoma

✍ Ryoichi Kyomoto; Hirobumi Kumazawa; Yoshinobu Toda; Noriko Sakaida; Akiharu Okam 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 332 KB 👁 2 views

To evaluate the prognostic significance of cyclin D1 protein/gene expressions in human head-and-neck squamous-cell carcinoma (HNSCC), we examined amplification of the cyclin-D1 gene (CCND1) by the differential PCR method and over-expression of cyclin-D1 protein by immunohistochemistry in 45 paraffin