A DFT study of Artemisinin and 1,2,4-trioxane
β Scribed by Jiande Gu; Kaixian Chen; Hualiang Jiang; Ruyun Ji
- Book ID
- 114143167
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 192 KB
- Volume
- 459
- Category
- Article
- ISSN
- 0166-1280
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter-and intramolecular reaction with a carbonyl compound
The vibrational spectra of some 1,2,4-trioxanes present two characteristic bands at 790 and 880 cm-'. On the basis of "0-isotopic substitution and comparison with analogous compounds, these bands have been assigned to coupled C-0 and 0-0 stretching modes of the C-0-0 element. ## Introduction. -Ev