Synthesis of a Diastereomerically Pure Racemic 1,2,4-Trioxane Dimer Related to Antiproliferative Dimers of Naturally Occurring Artemisinin.

Synthesis of Racemic Tricyclic 1,2,4-Tri

Synthesis of Racemic Tricyclic 1,2,4-Trioxanes that Are Isomeric to Simplified Analogues of Naturally Occurring Artemisinin.

✍ M. Yu. Krasavin; M. V. Dorogov 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 14 KB 👁 1 views

Other bioactive products U 1300 Synthesis of Racemic Tricyclic 1,2,4-Trioxanes that Are Isomeric to Simplified Analogues of Naturally Occurring Artemisinin. -Key step is the cyclization of a ketone-tethered enol ether to give the novel trioxane framework (II)/(III), simplified analogue of an artemis