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A detailed understanding of the enhanced hypothermic productivity of interferon-γ by Chinese-hamster ovary cells

✍ Scribed by Stephen R. Fox; Hong Kiat Tan; Mei Chee Tan; S. C. Niki C. Wong; Miranda G. S. Yap; Daniel I. C. Wang


Book ID
111718034
Publisher
Portland Press
Year
2005
Tongue
English
Weight
266 KB
Volume
41
Category
Article
ISSN
0885-4513

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We have established a novel production process which allows up to fourfold higher production of a model secreted protein, the human secreted alkaline phosphatase (SEAP), in Chinese hamster ovary (CHO) cells. A cytostatic production phase is established in which cell proliferation is inhibited or com