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Enhanced productivity of G1 phase Chinese hamster ovary cells using the GADD153 promoter

โœ Scribed by Leonore de Boer; Peter P. Gray; Noelle-Ann Sunstrom

Book ID
111573394
Publisher
Springer Netherlands
Year
2004
Tongue
English
Weight
273 KB
Volume
26
Category
Article
ISSN
0141-5492

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A novel cytostatic process enhances the
A novel cytostatic process enhances the productivity of Chinese hamster ovary cells
โœ Martin Fussenegger; Xenia Mazur; James E. Bailey ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 288 KB ๐Ÿ‘ 2 views

We have established a novel production process which allows up to fourfold higher production of a model secreted protein, the human secreted alkaline phosphatase (SEAP), in Chinese hamster ovary (CHO) cells. A cytostatic production phase is established in which cell proliferation is inhibited or com