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A convenient synthesis of the (±)-prelog-djerassi lactone from cyclopentanone

✍ Scribed by Christiane Santelli-Rouvier; Sophie Lefrère; Maurice Santelli


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
259 KB
Volume
35
Category
Article
ISSN
0040-4039

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A synthesis of (+)-Prelog-Djerassi Lacto
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A new approach to the synthesis of Prelog-Djerassi Lactonic acid (1) is reported. A key step in this synthesis involves an lreland-Claisen rearrangement/silicon-mediated fragmentation sequence to provide the carbon framework in (1).

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