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A convenient synthesis of racemic 6-hydroxyethyl-2-alkylthio-substituted penems

✍ Scribed by Frank DiNinno; David A. Muthard; Ronald W. Ratcliffe; Burton G. Christensen

Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 221 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87662-5

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✦ Synopsis

Racemic 6-hydroxyethyl-2-alkylsulfinylpenems undergo a facile displacement with mercaptans under basic conditions to conveniently provide new 2-alkylthiopenems.

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