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Synthesis of racemic, 2-(alkylthio)-6-(1-hydroxyethyl) penems; attempted penem synthesis via copper (I) - promoted cyclisations

โœ Scribed by S.W. McCombie; A.K. Ganguly; V.M. Girijavallabhan; P.D. Jeffrey; S. Lin; P. Pinto; A.T. McPhail


Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
233 KB
Volume
22
Category
Article
ISSN
0040-4039

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A convenient synthesis of racemic 6-hydr
โœ Frank DiNinno; David A. Muthard; Ronald W. Ratcliffe; Burton G. Christensen ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 221 KB

Racemic 6-hydroxyethyl-2-alkylsulfinylpenems undergo a facile displacement with mercaptans under basic conditions to conveniently provide new 2-alkylthiopenems.