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A convenient synthesis of 3-(4-pyridinyl)quinolines

✍ Scribed by Baldev Singh; George Y. Lesher

Book ID
112130113
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
104 KB
Volume
28
Category
Article
ISSN
0022-152X

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A new efficient synthesis of 3-(4-pyridi
A new efficient synthesis of 3-(4-pyridinyl)methylindoles
✍ Ping Zhou; Yanfang Li; Kristin L Meagher; Richard G Mewshaw; Boyd L Harrison πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 52 KB

A new efficient method for the preparation of 3-(4-pyridinyl)methylindoles has been developed. The new method involves coupling of indoles with 4-pyridinecarboxaldehyde to give 3-indolyl 4-pyridinyl methanols, which upon treatment with triethylsilane in the presence of trifluoroacetic acid afford 3-