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A convenient synthesis of 1-azabicycloalkanes and their lactams via cuprates of formamidines

✍ Scribed by Philip D. Edwards; A.I. Meyers

Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
162 KB
Volume
25
Category
Article
ISSN
0040-4039

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✍ Gwenaëlle Liberge; Stéphane Lebrun; Axel Couture; Pierre Grandclaudon 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 German ⚖ 192 KB

## Abstract A concise synthetic approach to functionalized __α__‐methylidenebutanolactams has been developed. The synthetic strategy is based on the preliminary assembly of the lactam template equipped with appropriate functionalities. Subsequent installation of the methylidene by a metalation/alky