𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Convenient Synthesis of Functionalized α-Methylidenebutano-4-lactams

✍ Scribed by Gwenaëlle Liberge; Stéphane Lebrun; Axel Couture; Pierre Grandclaudon

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
192 KB
Volume
94
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A concise synthetic approach to functionalized α‐methylidenebutanolactams has been developed. The synthetic strategy is based on the preliminary assembly of the lactam template equipped with appropriate functionalities. Subsequent installation of the methylidene by a metalation/alkylation/elimination sequence completed the elaboration of the racemic title compounds.

📜 SIMILAR VOLUMES

A convenient synthesis of macrocyclic la
A convenient synthesis of macrocyclic lactams
✍ Qian Ligang; Sun Zhong; Deffo Tamboue; Kristin Bowman Mertes 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 266 KB

## SuMMAfM A facile method is described for the synthesis of macrocyclk lactams using dkarboxytk adds and dtamines dtrectty in the presence of diphenyfphosphoryt a&b. Macrocyclk polyamines have been shown to complex a variety of inorganic and organic ions.1 Recent devebpments in ankn comptexatbn

A convenient synthesis of azetidine-2,3-
A convenient synthesis of azetidine-2,3-diones (α-Keto-β-Lactams)
✍ M.S Manhas; S.S Bari; B.M Bhawal; Ajay K Bose 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 188 KB

Summaryz Azetidine-2,3-dionee can be conveniently synthesized by mild hydrolysis of the product of the reaction between a-phenylthio-&la&ems and sulfuryl chloride.

A convenient synthesis of functionalized
A convenient synthesis of functionalized vinylepoxides
✍ P.Veeraraghavan Ramachandran; Marek P Krzeminski 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 152 KB

Functionalized vinylepoxides were synthesized, in high yields, from tx-bromoaldehydes and -ketones via vinylalumination, followed by cyclization with K2CO3 or KF under non-aqueous conditions.