A convenient preparation of 2-[15N]-amino-4,6-dimethoxypyrimidine
✍ Scribed by Thomas K. Spencer; Gunda I. Georg; Jeffrey Aubé
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 197 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
A convenient preparation of 2‐[^15^N]‐amino‐4,6‐dimethoxypyrimidine using ^15^N‐ammonium chloride as the source of ^15^N is described.
📜 SIMILAR VOLUMES
Condensation of guanidine-15N3 with 4-[ N( 2-amino-3-cyano-5-pyrazinylmethyl)-N-methylamino] benzoic acid (1) in refluxing methanol afforded 4amino-4-deoxy-N10-methylpteroic-3-15N-2-15NH2 (2). indicated no label introduction at the pterin N1 position. Coupling of 2. with diethyl L-gluatmate and subs
The Preparation of [15N,15N']-and [4,4'-13 C2]-4,4'-Dichloroazobenzene and [ , Nt]-4-Chloroazobenzene 15N 15
## Abstract ^15^N labeled tetranitromethane, C(^15^NO~2~)~4~, was prepared from anhydrous nitric acid and acetic anhydride. A procedure for the preparation of the nitric acid from Na^15^NO~3~ is described. Tyrosine was nitrated with H^15^NO~3~ and its ^15^N NMR spectrum compared well with that of t
## Abstract The title compounds have been prepared by a simple and economical procedure from the corresponding Bocprotected α‐benzyl esters and [^15^N]ammonia with N,N′‐carbonyldiimidazole as coupling agent. Catalytic hydrogenolysis furnished both labelled products in high overall yields suitable f