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A Convenient Oxazole C-2 Protecting Group: The Synthesis of 4- and 5-Substituted Oxazoles via Metalation of 2-Triisopropylsilyloxazoles.

✍ Scribed by Ross A. Miller; Randi M. Smith; Benjamin Marcune

Publisher
John Wiley and Sons
Year
2006
Weight
27 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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📜 SIMILAR VOLUMES

Synthesis of 2,4- and 2,5-Disubstituted
Synthesis of 2,4- and 2,5-Disubstituted Oxazoles via Metal- Catalyzed Cross-Coupling Reactions
✍ Carla M. Counceller; Chad C. Eichman; Nicolas Proust; James P. Stambuli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

## Abstract The rapid synthesis of 2,4‐ and 2,5‐disubstituted oxazoles __via__ metal‐catalyzed cross‐coupling reactions is reported. The 4‐ or 5‐position of the corresponding 4‐ or 5‐halogenated 2‐butylthiooxazoles was successfully functionalized __via__ Suzuki–Miyaura, Sonogashira and Stille cross